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CCR10 Antibody
Product Overview
Antibody Target: CCR10
Alternative Name: CCR10, CCR-10, CCR 10,CC chemokine receptor 10, chemokine (C-C motif) receptor 10, G protein-coupled receptor 2, GPCR2, GPCR 2, GPCR-2
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide surrounding amino acid 353 of human CCR10
Accession#: NP_057686
Gene ID: 2826
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification: Affinity purified
Species Reactivity: human, mouse
Application: Western blot
Application & Usage: Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The anti-CCR10 antibody recognizes 50 kDa human CCR10 in Western blot analysis.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: Recently, a function has been assigned to a previously identified orphan chemokine receptor, GPR-2. This receptor, also called CCR10, binds with monocyte chemoattractant protein (MCP)-1, MCP-3 and MIP-1 beta. CCR10 is expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells, T cells as well as in skin-derived Langerhans cells. CCR10 may play a role in both skin homeostasis as well as a potential role in inflammatory responses.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans. |