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IL-18, human recombinant
A proinflammatory cytokine
Product Overview
Alternate Names / Synonyms: Human IL-18, IL-18, IL18, IL 18, h-IL-18, rh-IL-18, recombinant human IL-18, recombinant IL-18, IL, interluekin
Gene Symbol: IL18
Accession #: Q14116
Gene ID: 3606
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized from PBS
Molecular Weight: 18.3 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by dose-dependent stimulation of the IFNg by human PBMC co-stimulated with rh-IL-12 was found to be 5 ng/ml.
Reconstitution Instructions: Reconstitute in ice-cold water to a concentration of 0.5-1 µg/µl. The solution can be stored at 4°C for 1 week. For storage, prepare appropriate aliquots and freeze them at –80°C for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: Interleukin-18 (IL-18), an 18 kDa cytokine, is a single, non-glycosylated polypeptide chain containing 157 amino acids. IL-18 was previously known as interferon-g inducing factor (IGIF). This pleiotropic cytokine is produced by monocyte/macrophage cells. Like IL-12, IL-18 plays an important role in cell-mediated immune responses.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |