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FGF-18, human recombinant
A heparin binding growth factor, stimulating the proliferation and activation of cells expressing FGFR
Product Overview
Alternate Names / Synonyms: human FGF-18, FGF-18, FGF18, FGF 18, h-FGF-18, rh-FGF-18, recombinant human FGF-18, recombinant FGF-18, FGF
Gene Symbol: FGF-18
Accession #: O76093
Gene ID: 8817
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized from 10 mM Tris pH 8.0. The protein may appear as a haze or film, which you may not see at the bottom of the vial.
Molecular Weight: 21.2 kDa
Purity by SDS-PAGE: ≥95%
Purity by HPLC: ≥95%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is <0.5 ng/ml, corresponding to a specific activity of >2 x 10⁶ units/mg.
Reconstitution Instructions: Reconstitute in 5 mM Tris, pH 8.0 to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: The FGFs plays an important role in regulating tissue growth, morphogenesis and tissue repair. FGF-18 is a newly discovered heparin binding growth factor that stimulates the proliferation and activation of cells that express FGF receptors. The human FGF-18 is a 21.2 kDa protein containing 182 amino acid residues.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |