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CNTF, human recombinant
A potent neural factor promoting survivability and differentiation of neuronal cell types.
Product Overview
Alternate Names / Synonyms: human CNTF, CNTF, h-CNTF, rh-CNTF, recombinant human CNTF, recombinant CNTF
Gene Symbol: CNTF
Accession #: P26441
Gene ID: 1270
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized without additives
Molecular Weight: 22.9 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by the dose-dependent proliferation of human TF-1 cells is < 2 ng/ml, corresponding to a specific activity of > 5 x 10⁵ units/mg.
Reconstitution Instructions: Reconstitute in 5 mM Sodium Phosphate, pH 7.5 to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: CNTF (Ciliary Neurotrophic Factor) is a potent neural factor that was originally characterized as a survivability factor for chick ciliary neurons in vitro. CNTF has also been shown to promote survivability and differentiation of other neuronal cell types. Recombinant human CNTF is a 22.9 kDa protein containing 200 amino acid residues
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |