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HSF1 Antibody
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Product OverviewAntibody Target: HSF
Alternative Name: HSF-1, HSF 1, Heat shock factor 1, Heat shock transcription factor 1 , HSTF1, HSTF 1
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide surrounding amino acid 515 of mouse HSF 1
Accession#: P38532
Gene ID: 15499
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification: Affinity purified
Species Reactivity: human, mouse
Positive Control: Western Blot: 3T3 cells & Jurkat cells
Application: Western blot, Immunohistochemistry
Application & Usage: The antibody can be used for Western blotting (0.5-4 µg/ml) and in Immunohistochemistry (5 µg/ml). However, the optimal conditions should be determined individually. The antibody detects ~60 and 130 kDa of Dystrophin in samples from human, mouse and rat origins. Reactivity to other species has not been determined. Blocking peptide (Cat. # 3812BP-50) is available separately.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: HSF 1 responds to cellular stress signals such as heat, heavy metals and oxidative reagents. It binds to heat shock response elements in the upstream region of heat shock gene and activates transcription. Upon activation, HSF 1 is trimerized and is localized in the nucleus where it binds the DNA.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans. |