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PPAR gamma Antibody
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Product Overview
Antibody Target: PPAR
Alternative Name: PPARG, PPAR G, PPAR g, peroxisome proliferator activated receptor
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide surrounding amino acid 262 of human PPARg isoform CRA-c
Accession#: P37231
Gene ID: 5468
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification: Affinity purified
Species Reactivity: human, mouse
Application: Western blot
Application & Usage: Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~33 kDa band, corresponding to PPARg (isoform CRA-c) in samples from human and mouse origins. Reactivity to other species has not been tested.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: PPAR (Peroxisome proliferator-activated receptor) is a member of the nuclear hormone receptor superfamily and functions as a transcriptional activator. PPARg is preferentially expressed in adipocyte as well as in vascular smooth muscle cells and macrophage. Besides its role in mediating adipogenesis and lipids metabolism, PPARg also modulates insulin sensitivity, cell proliferation and inflammation. The inhibition of PPARg transcription activity is due to MAP kinase phosphorylation at serine 84 of PPARg.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans. |