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Phorbol-12-myristate 13-acetate (PMA)
Product Overview
Product Name: Phorbol-12-myristate 13-acetate (PMA)
Alternate Name/Synonyms: PMA, 12-O-Tetradecanoylphorbol 13-acetate,TPA, 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate
Description: This is the most commonly used phorbol ester. It binds to and activates protein kinase C, causes an extremely wide range of effects in cells and tissues and is a very potent mouse skin tumor promoter. Inhibits apoptosis induced by the Fas antigen, but induced apoptosis in HL-60 promyelocytic leukemia cells
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 16561-29-8
Molecular Formula: C₃₆H₅₆O₈
Molecular Weight: 616.83
Purity: >99%
Solubility:DMSO or EtOH
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from light
SMILES: CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
InChi: InChI=1S/C36H56O8/c1-7-8-9-10-11-12-13-14-15-16-17-18-29(39)43-32-24(3)35(42)27(30-33(5,6)36(30,32)44-25(4)38)20-26(22-37)21-34(41)28(35)19-23(2)31(34)40/h19-20,24,27-28,30,32,37,41-42H,7-18,21-22H2,1-6H3/t24-,27+,28-,30-,32-,34-,35-,36-/m1/s1
InChi Key: PHEDXBVPIONUQT-RGYGYFBISA-N
PubChem CID: 27924
MDL Number: MFCD00036736
USAGE: For Research Use Only! Not For Use in Humans. |