Caspase-9 Inhibitor Z-LEHD-FMK
Product Overview
Product Name: Caspase-9 Inhibitor Z-LEHD-FMK
Alternate Name/Synonyms: Z-LEHD-FMK, Caspase-9 Inhibitor, LEHD-fluoromethylketone
Description: A synthetic peptide that irreversibly inhibits caspase-9 and related caspase activity. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Peptide Sequence: Z-Leu-Glu(OMe)-His-Asp(OMe)-FMK
Appearance: Liquid
Formulation: DMSO ( 2 mM)
CAS Number: N/A
Molecular Formula: C₃₂H₄₃FN₆O₁₀
Molecular Weight: 690.7
Purity: >98% by HPLC
Solubility:N/A
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from light and moisture
SMILES: CC(C)CC(C(=O)NC(CCC(=O)OC)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC2=CC=CC=C2
InChi: InChI=1S/C32H43FN6O10/c1-19(2)12-24(39-32(46)49-17-20-8-6-5-7-9-20)30(44)36-22(10-11-27(41)47-3)29(43)38-25(13-21-16-34-18-35-21)31(45)37-23(26(40)15-33)14-28(42)48-4/h5-9,16,18-19,22-25H,10-15,17H2,1-4H3,(H,34,35)(H,36,44)(H,37,45)(H,38,43)(H,39,46)
InChi Key: YXRKBEPGVHOXSV-UHFFFAOYSA-N
PubChem CID: 44135217
MDL Number: MFCD01862609
USAGE: For Research Use Only! Not For Use in Humans. |