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Staurosporine
Product Overview
Product Name: Staurosporine
Alternate Name/Synonyms: Antibiotic AM-2282
Description: Potent inhibitor of protein kinase C and most other kinases, including tyrosine kinases. Inhibits topoisomerase II directly by blocking transfer of phosphodiester bonds from DNA to active site tyrosine. Induces apoptosis in CHO cells at 1 µM.
Peptide Sequence: N/A
Appearance: Pale yellow solid
Formulation: N/A
CAS Number: 62996-74-1
Molecular Formula: C₂₈H₂₆N₄O₃
Molecular Weight: 466.53
Purity: >99% by TLC
Solubility:DMSO ( 25 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: RT
Handling: Protect from light and moisture
SMILES: CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
InChi: InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m0/s1
InChi Key: HKSZLNNOFSGOKW-HMWZOHBLSA-N
PubChem CID: 451705
MDL Number: MFCD00077402
USAGE: For Research Use Only! Not For Use in Humans. |