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Cycloheximide (100 mM)
Product Overview
Product Name: Cycloheximide (100 mM)
Alternate Name/Synonyms: 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide, Actidione, Naramycin A
Description: A very active antibiotic against many yeasts and fungi. Inhibits protein synthesis in eukaryotes (but not in prokaryotes) by interfering with the translocation step. It inhibits chain initiation as well as chain elongation by acting on the 60S subunit of the eukaryote ribosome, interacting directly with enzyme translocase. Cycloheximide is used as an inhibitor to study cell-free protein biosynthesis in eukaryotes and also used to block ribosome-dependent in vivo polypeptide synthesis. It induces apoptosis in a variety of cells, but can also delay or inhibit apoptosis by other agents.
Peptide Sequence: N/A
Appearance: Liquid
Formulation: DMSO ( 100 mM)
CAS Number: 66-81-9
Molecular Formula: C₁₅H₂₃NO₄
Molecular Weight: 281.35
Purity: >95%
Solubility:N/A
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from light and moisture
SMILES: CC1CC(C(=O)C(C1)C(CC2CC(=O)NC(=O)C2)O)C
InChi: InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1
InChi Key: YPHMISFOHDHNIV-FSZOTQKASA-N
PubChem CID: 6197
MDL Number: MFCD00082346
USAGE: For Research Use Only! Not For Use in Humans. |