|
Cathepsin D (active, human)
An active Lysosomal aspartyl protease
Product Overview
Alternate Names / Synonyms: Cathepsin, Cathepsin D, Active Cathepsin D, Cathepsin Protein, Cathepsin D Protein, cathepsin D assay, cathepsin assay
Gene Symbol: CTSB
Accession #: P07339
Gene ID: 1509
Source: Human liver
Appearance: Lyophilized
Physical Form Description: Lyophilized from a solution containing 2 mM sodium phosphate, pH 6.5
Molecular Weight: N/A
Purity by SDS-PAGE: ≥95%
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: 365 units/mg
Reconstitution Instructions: Reconstitute the vial in water to a concentration of 0.1-1 µg/µl. Aliquot and refreeze at -80°C immediately for future use.
Storage Temp.: -80°C
Shipping: Gel Pack
Background Information: Cathepsin D is an estrogen-regulated protein associated with tissue breakdown. Levels of cathepsin D have been positively correlated with recurring breast cancers of both node negative and node positive types. Additionally cathepsin D has been associated with amyloid formation in Alzheimer’s plaques. As cathepsin D activity is increased by cigarette smoke, the enzyme may contribute to lung tissue damage in smokers.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans. |