细胞松弛素 D Cytochalasin D
产品编号:C8273
产品名称:细胞松弛素 D Cytochalasin D
供应商:Sigma
规格: 1MG
目录价:2301
CAS编号:22144-77-0
产品编号 C8273
CAS号 22144-77-0
细胞松弛素 D Cytochalasin D
from Zygosporium mansonii, ≥98% (TLC and HPLC), powder
别名: 松胞菌素 D
经验分子式(希尔表示法) C30H37NO6
分子量 507.62
Biochem/physiol Actions
肌动蛋白聚合化的强效抑制剂;破坏肌动蛋白微丝;活化 p53 依赖性途径;抑制平滑肌收缩;抑制胰岛素刺激的糖转运。
Cell permeable fungal toxin; potent inhibitor of actin polymerization. Disrupts actin microfilaments and activates the p53-dependent pathways causing arrest of the cell cycle at the G1-S transition. Inhibits smooth muscle contraction. Inhibits insulin-stimulated, but not basal, transport of glucose.
biological source from Zygosporium mansonii
assay ≥98% (TLC and HPLC)
form powder
solubility DMSO: soluble
ethanol: soluble
storage temp. -20度