中文名:卡铂
英文名称:Carboplatin
分子式 :C6H12N2O4Pt
CAS No.:41575-94-4
用途:抗肿瘤
性状:白色结晶粉末
Sigma相关产品资料:
Sigma C2538 Carboplatin
Synonym:cis-Diammine(1,1-cyclobutanedicarboxylato) platinum
CAS Number:41575-94-4
Linear Formula: [C4H6(CO2)2]Pt(NH3)2
Molecular Weight:371.25
EC Number:255-446-0
MDL number:MFCD00070464
PubChem Substance ID:24278303
Description
Biochem/physiol Actions Carboplatin is a platinum-based antineoplastic drug that damages DNA by forming intrastrand cross-links with neighboring guanine residues. Tumors acquire resistance to these drugs through the loss of DNA-mismatch repair (MMR) activity and the resultant decrease in the induction of programmed cell death.