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正品现货|Cyclosporin A|Cyclosporin|Sandimmune|≥95
发布人:浩然生物
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5936次【字号 大 中 小】 发布时间:2011年08月17日
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英文名:Ciclosporin A,CsA,Cs-A,CY-A,Sandimmune,Ciclosporin,Cyspin. 中文名:环孢多肽A;环孢灵;环孢霉素A;赛斯平;山地明 ,环孢素,新山地明,环孢素A Sigma相关产品资料: Sigma C3662 Cyclosporin A from Tolypocladium inflatum, ≥95% (HPLC), solid Synonym:Antibiotic S 7481F1, Cyclosporine CAS Number:59865-13-3 Linear Formula:C62H111N11O12 Molecular Weight:1202.61 Beilstein Registry Number:3647785 MDL number: MFCD00274558 PubChem Substance ID:24278028 Description Biochem/physiol Actions A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα. Can block cytochrome c release from mitochondria. Properties biological sourcefrom Tolypocladium inflatum assay≥95% (HPLC) form solid color white solubility dichloromethane: 10 mg/mL ethanol: 10 mg/mL DMSO: 50 mg/mL chloroform: 6 mg/mL H2O: insoluble Gene Information human ... PPP3CA(5530), PPP3CB(5532), PPP3CC(5533), PPP3R1(5534), PPP3R2(5535) storage temp. 2-8°C
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