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正品现货|Cyclosporin A|Cyclosporin|Sandimmune|≥95

发布人:浩然生物 浏览 5936次【字号 】 发布时间:2011年08月17日 打印本页

货号 产品名称 厂家 规格 单价 详细 订购
C3662 Cyclosporin A (环胞霉素A,环孢霉素A) Sigma 5MG 1250 详细查看 订购
C3662 Cyclosporin A (环胞霉素A,环孢霉素A) Sigma 10MG 2280 详细查看 订购
英文名:Ciclosporin A,CsA,Cs-A,CY-A,Sandimmune,Ciclosporin,Cyspin.
中文名:环孢多肽A;环孢灵;环孢霉素A;赛斯平;山地明 ,环孢素,新山地明,环孢素A
Sigma相关产品资料:
Sigma C3662 Cyclosporin A
from Tolypocladium inflatum, ≥95% (HPLC), solid
Synonym:Antibiotic S 7481F1, Cyclosporine
CAS Number:59865-13-3
Linear Formula:C62H111N11O12
Molecular Weight:1202.61
Beilstein Registry Number:3647785
MDL number: MFCD00274558
PubChem Substance ID:24278028
Description
Biochem/physiol Actions
 A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα. Can block cytochrome c release from  mitochondria.
Properties
biological sourcefrom Tolypocladium inflatum
assay≥95% (HPLC)
form solid
color white
solubility dichloromethane: 10 mg/mL
ethanol: 10 mg/mL
DMSO: 50 mg/mL
chloroform: 6 mg/mL
H2O: insoluble
Gene Information human ... PPP3CA(5530), PPP3CB(5532), PPP3CC(5533), PPP3R1(5534), PPP3R2(5535)
storage temp. 2-8°C


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