产品编号:ant-bl-1
产品名称:Blasticidin S (solution)
供应商:Invivogen
规格: 100 mg (5 x 2 ml)
目录价:3080
库存状态: 现货
应用范围:生化试验
相关信息:
Blasticidin
Blasticidin is an efficient selective antibiotic that acts on both eukaryotic and prokaryotic cells. Blasticidin is a peptidyl nucleoside antibiotic isolated from Streptomyces griseochromogenes that inhibits protein synthesis by interfering with the peptide-bond formation in the ribosomal machinery.
Resistance to blasticidin is conferred by the blasticidin resistance gene from Bacillus cereus (bsr), which codes for blasticidin-S deaminase.
Cell death induced by blasticidin is rapid and cell lines carrying a blasticidin resistance gene can be obtained in less than a week. Typically, mammalian cells are sensitive to blasticidin concentrations of 1-10 μg/ml, and bacteria to 25-100 μg/ml.
Working concentration:
- 25-100 μg/ml in bacteria
- 1-30 μg/ml in mammalian cells
Purity: controlled by HPLC >95%
Formula: C17H26N8O5, 1 HCl
Quality control:
Blasticidin hydrochloride is supplied as colorless solution in HEPES buffer (100% active compound), pH 7.5, filtered to sterility for customer convenience and cell culture tested, or as a powder.
Activity controlled by bioassays on bacteria and mammalian cell lines.
MDL Number: MFCD02091640
USAGE: For Research Use Only! Not For Use in Humans.